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Understanding Side Effects
TABRECTA® (capmatinib) tablets

Side effects with TABRECTA
It’s only natural to have concerns about potential side effects when starting a new treatment. TABRECTA may have some side effects with which you’re unfamiliar. Talk to your health care provider about any side effects you’re experiencing. If you develop certain serious side effects, your health care provider may decrease your dose, have you take a break from treatment, or have you stop taking TABRECTA.
What are the possible side effects of TABRECTA?
TABRECTA may cause serious side effects, including:

Lung or breathing problems
TABRECTA may cause inflammation of the lungs that can cause death. Tell your health care provider right away if you develop any new or worsening symptoms, including:
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cough
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fever
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trouble breathing or shortness of breath
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Your health care provider may temporarily stop or permanently stop treatment with TABRECTA if you develop lung or breathing problems during treatment.

Liver problems
TABRECTA may cause abnormal liver blood test results. Your health care provider will do blood tests to check your liver function before you start treatment and during treatment with TABRECTA. Tell your health care provider right away if you develop any signs and symptoms of liver problems, including:
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your skin or the white part of your eyes turns yellow (jaundice)
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dark or “tea-colored” urine
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light-colored stools (bowel movements)
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confusion
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tiredness
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loss of appetite for several days or longer
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nausea and vomiting
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pain, aching, or tenderness on the right side of your stomach area (abdomen)
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weakness
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swelling in your stomach area
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Your health care provider may change your dose, temporarily stop, or permanently stop treatment with TABRECTA if you develop liver problems during treatment.

Risk of sensitivity to sunlight (photosensitivity)
Your skin may be sensitive to the sun (photosensitivity) during treatment with TABRECTA. Use sunscreen or wear clothes that cover your skin during your treatment with TABRECTA to limit direct sunlight exposure
What are the most common side effects of TABRECTA?
The most common side effects of TABRECTA include:
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Swelling of your hands or feet
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Nausea
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Tiredness and weakness
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Vomiting
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Loss of appetite
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Changes in certain blood tests
These are not all of the possible side effects of TABRECTA. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.